The short answer
Levothyroxine has no single cash price. Your total depends on the exact product, pharmacy, quantity, insurance, and offer. The CMS numbers below are pharmacy acquisition benchmarks—not patient prices.
Before you compare Levothyroxine
Copy the exact product name and strength, including mcg, from your label. Ask your pharmacist before changing the manufacturer or product.
Levothyroxine acquisition-cost reference
One representative NDC per description. Values retain five decimal places so low per-unit costs do not round to zero. EA means “each”; confirm the dispensing unit and package with your pharmacist.
Snapshot retrieved 2026-09-22. Individual record dates appear below.
| Product description / NDC | NADAC per unit | Unit | As of |
|---|---|---|---|
| levothyroxine 100 mcg tabletNDC 00378180910 · Generic | $0.05073 | EA | |
| levothyroxine 112 mcg tabletNDC 00378181110 · Generic | $0.05894 | EA | |
| levothyroxine 125 mcg tabletNDC 00378181310 · Generic | $0.05705 | EA | |
| levothyroxine 137 mcg tabletNDC 00378182310 · Generic | $0.06273 | EA | |
| levothyroxine 150 mcg tabletNDC 00378181510 · Generic | $0.05968 | EA | |
| levothyroxine 175 mcg tabletNDC 00378181710 · Generic | $0.07654 | EA | |
| levothyroxine 200 mcg tabletNDC 00378181910 · Generic | $0.08017 | EA | |
| levothyroxine 25 mcg tabletNDC 00378180010 · Generic | $0.03568 | EA | |
| levothyroxine 300 mcg tabletNDC 00378182177 · Generic | $0.09986 | EA | |
| levothyroxine 50 mcg tabletNDC 00378180310 · Generic | $0.04062 | EA | |
| levothyroxine 75 mcg tabletNDC 00378180510 · Generic | $0.04633 | EA | |
| levothyroxine 88 mcg tabletNDC 00378180710 · Generic | $0.05015 | EA |
Original CMS dataset · Download this reference as JSON · How we select records
Acquisition benchmark history
Observed CMS acquisition costs for pharmacies, not prices patients pay. We compare only the same NDC, description, classification, and unit. No retail savings are inferred. Archive, downloads, and history methodology.
levothyroxine 100 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378180910 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.05073 | JSON |
levothyroxine 112 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378181110 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.05894 | JSON |
levothyroxine 125 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378181310 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.05705 | JSON |
levothyroxine 137 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378182310 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.06273 | JSON |
levothyroxine 150 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378181510 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.05968 | JSON |
levothyroxine 175 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378181710 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.07654 | JSON |
levothyroxine 200 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378181910 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.08017 | JSON |
levothyroxine 25 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378180010 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.03568 | JSON |
levothyroxine 300 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378182177 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.09986 | JSON |
levothyroxine 50 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378180310 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.04062 | JSON |
levothyroxine 75 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378180510 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.04633 | JSON |
levothyroxine 88 mcg tablet · Baseline only — no earlier comparable source date
NDC 00378180710 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.05015 | JSON |
Get a price for your prescription
- Match the label. Write down the full product name, strength, dosage form, and quantity. Ask the pharmacy about the package if you are unsure.
- Ask for separate totals. Get the cash price, insurance price, and any discount offer for the same fill.
- Include required fees. Add delivery or membership costs that are not already included in the quote.
- Compare and confirm. Use your actual quotes in the calculator and ask your plan about the effect on your benefit.
A question to bring to the counter
“Could you check the cash total and my insurance cost for my prescribed Levothyroxine, with the same strength, form, and quantity? Are there any extra fees, and is this the final price for this fill?”
Common questions
How much does Levothyroxine cost without insurance?
RxCompare does not have a live retail quote for Levothyroxine. Request the cash total for your prescribed strength, form, and quantity from a pharmacy. The table on this page is an acquisition-cost reference, not an amount you can expect to pay.
Can I compare different Levothyroxine strengths?
Use the exact prescribed product for a fair price comparison. Do not change strength, form, or release type based on a benchmark; ask your clinician or pharmacist about medication changes.
Why is my pharmacy quote different from this table?
The table reports a dated national acquisition benchmark for one representative NDC per description. Your pharmacy may stock another package or manufacturer, and retail pricing includes more than acquisition cost.
Sources & further reading
Source links checked 2026-09-22. Cost information only; this content has not been clinically reviewed.