The short answer

Zepbound has no single cash price. Your total depends on the exact product, pharmacy, quantity, insurance, and offer. The CMS numbers below are pharmacy acquisition benchmarks—not patient prices.

Before you compare Zepbound

Device and package differences can change the quoted total. Do not multiply a per-unit benchmark into an assumed retail price or course of treatment.

Product descriptions12
Pricing unitsML
SourceCMS NADAC

Zepbound acquisition-cost reference

One representative NDC per description. Values retain five decimal places so low per-unit costs do not round to zero. EA = each; ML = milliliter; GM = gram. A unit is not necessarily a complete package.

Snapshot retrieved 2026-09-22. Individual record dates appear below.

Zepbound CMS NADAC records · not retail prices
Product description / NDCNADAC per unitUnitAs of
zepbound 10 mg/0.5 ml penNDC 00002247180 · Brand$525.77168ML
zepbound 10 mg/dose (40 mg/2.4 ml) kwikpenNDC 00002353301 · Brand$281.35833ML
zepbound 12.5 mg/0.5 ml penNDC 00002246080 · Brand$525.77108ML
zepbound 12.5 mg/dose (50 mg/2.4 ml) kwikpenNDC 00002352201 · Brand$282.51359ML
zepbound 15 mg/0.5 ml penNDC 00002245780 · Brand$525.70244ML
zepbound 15 mg/dose (60 mg/2.4 ml) kwikpenNDC 00002351101 · Brand$280.02617ML
zepbound 2.5 mg/0.5 ml penNDC 00002250680 · Brand$526.11368ML
zepbound 2.5 mg/dose (10 mg/2.4 ml) kwikpenNDC 00002356601 · Brand$200.95020ML
zepbound 5 mg/0.5 ml penNDC 00002249580 · Brand$526.01388ML
zepbound 5 mg/dose (20 mg/2.4 ml) kwikpenNDC 00002355501 · Brand$200.90161ML
zepbound 7.5 mg/0.5 ml penNDC 00002248480 · Brand$525.77867ML
zepbound 7.5 mg/dose (30 mg/2.4 ml) kwikpenNDC 00002354401 · Brand$200.69510ML

Original CMS dataset · Download this reference as JSON · How we select records

Acquisition benchmark history

Observed CMS acquisition costs for pharmacies, not prices patients pay. We compare only the same NDC, description, classification, and unit. No retail savings are inferred. Archive, downloads, and history methodology.

zepbound 10 mg/0.5 ml pen · Baseline only — no earlier comparable source date

NDC 00002247180 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 10 mg/0.5 ml pen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$525.77168JSON
zepbound 10 mg/dose (40 mg/2.4 ml) kwikpen · Baseline only — no earlier comparable source date

NDC 00002353301 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 10 mg/dose (40 mg/2.4 ml) kwikpen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$281.35833JSON
zepbound 12.5 mg/0.5 ml pen · Baseline only — no earlier comparable source date

NDC 00002246080 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 12.5 mg/0.5 ml pen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$525.77108JSON
zepbound 12.5 mg/dose (50 mg/2.4 ml) kwikpen · Baseline only — no earlier comparable source date

NDC 00002352201 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 12.5 mg/dose (50 mg/2.4 ml) kwikpen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$282.51359JSON
zepbound 15 mg/0.5 ml pen · Baseline only — no earlier comparable source date

NDC 00002245780 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 15 mg/0.5 ml pen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$525.70244JSON
zepbound 15 mg/dose (60 mg/2.4 ml) kwikpen · Baseline only — no earlier comparable source date

NDC 00002351101 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 15 mg/dose (60 mg/2.4 ml) kwikpen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$280.02617JSON
zepbound 2.5 mg/0.5 ml pen · Baseline only — no earlier comparable source date

NDC 00002250680 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 2.5 mg/0.5 ml pen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$526.11368JSON
zepbound 2.5 mg/dose (10 mg/2.4 ml) kwikpen · Baseline only — no earlier comparable source date

NDC 00002356601 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 2.5 mg/dose (10 mg/2.4 ml) kwikpen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$200.95020JSON
zepbound 5 mg/0.5 ml pen · Baseline only — no earlier comparable source date

NDC 00002249580 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 5 mg/0.5 ml pen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$526.01388JSON
zepbound 5 mg/dose (20 mg/2.4 ml) kwikpen · Baseline only — no earlier comparable source date

NDC 00002355501 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 5 mg/dose (20 mg/2.4 ml) kwikpen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$200.90161JSON
zepbound 7.5 mg/0.5 ml pen · Baseline only — no earlier comparable source date

NDC 00002248480 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 7.5 mg/0.5 ml pen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$525.77867JSON
zepbound 7.5 mg/dose (30 mg/2.4 ml) kwikpen · Baseline only — no earlier comparable source date

NDC 00002354401 · ML · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for zepbound 7.5 mg/dose (30 mg/2.4 ml) kwikpen
Source dateFirst retrievedUSD per MLSnapshot
2026-09-162026-09-22$200.69510JSON

Get a price for your prescription

  1. Match the label. Write down the full product name, strength, dosage form, and quantity. Ask the pharmacy about the package if you are unsure.
  2. Ask for separate totals. Get the cash price, insurance price, and any discount offer for the same fill.
  3. Include required fees. Add delivery or membership costs that are not already included in the quote.
  4. Compare and confirm. Use your actual quotes in the calculator and ask your plan about the effect on your benefit.
Compare my Zepbound costs

A question to bring to the counter

“Could you check the cash total and my insurance cost for my prescribed Zepbound, with the same strength, form, and quantity? Are there any extra fees, and is this the final price for this fill?”

Common questions

How much does Zepbound cost without insurance?

RxCompare does not have a live retail quote for Zepbound. Request the cash total for your prescribed strength, form, and quantity from a pharmacy. The table on this page is an acquisition-cost reference, not an amount you can expect to pay.

Can I compare different Zepbound strengths?

Use the exact prescribed product for a fair price comparison. Do not change strength, form, or release type based on a benchmark; ask your clinician or pharmacist about medication changes.

Why is my pharmacy quote different from this table?

The table reports a dated national acquisition benchmark for one representative NDC per description. Your pharmacy may stock another package or manufacturer, and retail pricing includes more than acquisition cost.

Sources & further reading

Source links checked 2026-09-22. Cost information only; this content has not been clinically reviewed.