The short answer

Omeprazole has no single cash price. Your total depends on the exact product, pharmacy, quantity, insurance, and offer. The CMS numbers below are pharmacy acquisition benchmarks—not patient prices.

Before you compare Omeprazole

Prescription and over-the-counter packages can differ. Match the strength, delayed-release description, quantity, and prescription product with your pharmacist.

Product descriptions8
Pricing unitsEA
SourceCMS NADAC

Omeprazole acquisition-cost reference

One representative NDC per description. Values retain five decimal places so low per-unit costs do not round to zero. EA means “each”; confirm the dispensing unit and package with your pharmacist.

Snapshot retrieved 2026-09-22. Individual record dates appear below.

Omeprazole CMS NADAC records · not retail prices
Product description / NDCNADAC per unitUnitAs of
omeprazole dr 10 mg capsuleNDC 16714063001 · Generic$0.08157EA
omeprazole dr 20 mg capsuleNDC 00781286810 · Generic$0.02768EA
omeprazole dr 20 mg odtNDC 00113052055 · Generic$0.44354EA
omeprazole dr 20 mg tabletNDC 00536144813 · Generic$0.39042EA
omeprazole dr 40 mg capsuleNDC 16714012301 · Generic$0.04942EA
omeprazole mag dr 20 mg capNDC 83324011714 · Generic$0.40818EA
omeprazole mag dr 20 mg tabletNDC 00536132213 · Generic$0.45943EA
omeprazole mag dr 20.6 mg capNDC 55111039727 · Generic$0.40818EA

Original CMS dataset · Download this reference as JSON · How we select records

Acquisition benchmark history

Observed CMS acquisition costs for pharmacies, not prices patients pay. We compare only the same NDC, description, classification, and unit. No retail savings are inferred. Archive, downloads, and history methodology.

omeprazole dr 10 mg capsule · Baseline only — no earlier comparable source date

NDC 16714063001 · EA · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for omeprazole dr 10 mg capsule
Source dateFirst retrievedUSD per EASnapshot
2026-09-162026-09-22$0.08157JSON
omeprazole dr 20 mg capsule · Baseline only — no earlier comparable source date

NDC 00781286810 · EA · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for omeprazole dr 20 mg capsule
Source dateFirst retrievedUSD per EASnapshot
2026-09-162026-09-22$0.02768JSON
omeprazole dr 20 mg odt · Baseline only — no earlier comparable source date

NDC 00113052055 · EA · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for omeprazole dr 20 mg odt
Source dateFirst retrievedUSD per EASnapshot
2026-09-162026-09-22$0.44354JSON
omeprazole dr 20 mg tablet · Baseline only — no earlier comparable source date

NDC 00536144813 · EA · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for omeprazole dr 20 mg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-09-162026-09-22$0.39042JSON
omeprazole dr 40 mg capsule · Baseline only — no earlier comparable source date

NDC 16714012301 · EA · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for omeprazole dr 40 mg capsule
Source dateFirst retrievedUSD per EASnapshot
2026-09-162026-09-22$0.04942JSON
omeprazole mag dr 20 mg cap · Baseline only — no earlier comparable source date

NDC 83324011714 · EA · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for omeprazole mag dr 20 mg cap
Source dateFirst retrievedUSD per EASnapshot
2026-09-162026-09-22$0.40818JSON
omeprazole mag dr 20 mg tablet · Baseline only — no earlier comparable source date

NDC 00536132213 · EA · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for omeprazole mag dr 20 mg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-09-162026-09-22$0.45943JSON
omeprazole mag dr 20.6 mg cap · Baseline only — no earlier comparable source date

NDC 55111039727 · EA · 1 source date. Missing observations are not interpolated.

Recorded acquisition benchmarks for omeprazole mag dr 20.6 mg cap
Source dateFirst retrievedUSD per EASnapshot
2026-09-162026-09-22$0.40818JSON

Get a price for your prescription

  1. Match the label. Write down the full product name, strength, dosage form, and quantity. Ask the pharmacy about the package if you are unsure.
  2. Ask for separate totals. Get the cash price, insurance price, and any discount offer for the same fill.
  3. Include required fees. Add delivery or membership costs that are not already included in the quote.
  4. Compare and confirm. Use your actual quotes in the calculator and ask your plan about the effect on your benefit.
Compare my Omeprazole costs

A question to bring to the counter

“Could you check the cash total and my insurance cost for my prescribed Omeprazole, with the same strength, form, and quantity? Are there any extra fees, and is this the final price for this fill?”

Common questions

How much does Omeprazole cost without insurance?

RxCompare does not have a live retail quote for Omeprazole. Request the cash total for your prescribed strength, form, and quantity from a pharmacy. The table on this page is an acquisition-cost reference, not an amount you can expect to pay.

Can I compare different Omeprazole strengths?

Use the exact prescribed product for a fair price comparison. Do not change strength, form, or release type based on a benchmark; ask your clinician or pharmacist about medication changes.

Why is my pharmacy quote different from this table?

The table reports a dated national acquisition benchmark for one representative NDC per description. Your pharmacy may stock another package or manufacturer, and retail pricing includes more than acquisition cost.

Sources & further reading

Source links checked 2026-09-22. Cost information only; this content has not been clinically reviewed.