The short answer
Sertraline has no single cash price. Your total depends on the exact product, pharmacy, quantity, insurance, and offer. The CMS numbers below are pharmacy acquisition benchmarks—not patient prices.
Before you compare Sertraline
Check whether your prescription is for tablets or an oral concentrate. A price per milliliter cannot be compared directly with a price per tablet.
Sertraline acquisition-cost reference
One representative NDC per description. Values retain five decimal places so low per-unit costs do not round to zero. EA = each; ML = milliliter; GM = gram. A unit is not necessarily a complete package.
Snapshot retrieved 2026-09-22. Individual record dates appear below.
| Product description / NDC | NADAC per unit | Unit | As of |
|---|---|---|---|
| sertraline 150 mg capsuleNDC 47781095130 · Generic | $1.38295 | EA | |
| sertraline 20 mg/ml oral concNDC 16714060102 · Generic | $0.39651 | ML | |
| sertraline 200 mg capsuleNDC 47781096230 · Generic | $1.98830 | EA | |
| sertraline hcl 100 mg tabletNDC 00904692661 · Generic | $0.05042 | EA | |
| sertraline hcl 25 mg tabletNDC 00904692461 · Generic | $0.02818 | EA | |
| sertraline hcl 50 mg tabletNDC 00904692561 · Generic | $0.03445 | EA |
Original CMS dataset · Download this reference as JSON · How we select records
Acquisition benchmark history
Observed CMS acquisition costs for pharmacies, not prices patients pay. We compare only the same NDC, description, classification, and unit. No retail savings are inferred. Archive, downloads, and history methodology.
sertraline 150 mg capsule · Baseline only — no earlier comparable source date
NDC 47781095130 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $1.38295 | JSON |
sertraline 20 mg/ml oral conc · Baseline only — no earlier comparable source date
NDC 16714060102 · ML · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per ML | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.39651 | JSON |
sertraline 200 mg capsule · Baseline only — no earlier comparable source date
NDC 47781096230 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $1.98830 | JSON |
sertraline hcl 100 mg tablet · Baseline only — no earlier comparable source date
NDC 00904692661 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.05042 | JSON |
sertraline hcl 25 mg tablet · Baseline only — no earlier comparable source date
NDC 00904692461 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.02818 | JSON |
sertraline hcl 50 mg tablet · Baseline only — no earlier comparable source date
NDC 00904692561 · EA · 1 source date. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-09-16 | 2026-09-22 | $0.03445 | JSON |
Get a price for your prescription
- Match the label. Write down the full product name, strength, dosage form, and quantity. Ask the pharmacy about the package if you are unsure.
- Ask for separate totals. Get the cash price, insurance price, and any discount offer for the same fill.
- Include required fees. Add delivery or membership costs that are not already included in the quote.
- Compare and confirm. Use your actual quotes in the calculator and ask your plan about the effect on your benefit.
A question to bring to the counter
“Could you check the cash total and my insurance cost for my prescribed Sertraline, with the same strength, form, and quantity? Are there any extra fees, and is this the final price for this fill?”
Common questions
How much does Sertraline cost without insurance?
RxCompare does not have a live retail quote for Sertraline. Request the cash total for your prescribed strength, form, and quantity from a pharmacy. The table on this page is an acquisition-cost reference, not an amount you can expect to pay.
Can I compare different Sertraline strengths?
Use the exact prescribed product for a fair price comparison. Do not change strength, form, or release type based on a benchmark; ask your clinician or pharmacist about medication changes.
Why is my pharmacy quote different from this table?
The table reports a dated national acquisition benchmark for one representative NDC per description. Your pharmacy may stock another package or manufacturer, and retail pricing includes more than acquisition cost.
Sources & further reading
Source links checked 2026-09-22. Cost information only; this content has not been clinically reviewed.